Genomics, Proteomics and Bioinformatics (GPB) is interested in submissions across all areas of life science, biology, and biomedicine, focusing on large data acquisition, analysis, and curation.

Submission Deadline: October 31, 2024

The journal Genomics, Proteomics & Bioinformatics (GPB) is inviting submissions for a special issue (to be published in the Spring of 2025) on the topic of “Long-read Sequencing”.

Long-read sequencing (LRS) technologies are revolutionizing the field of genomics by providing unprecedented insights into genome architecture and function. With the ability to read long fragments of DNA and RNA, LRS overcomes many of the limitations of short-read sequencing, offering a more comprehensive view of genomic, epigenomic, and transcriptomic variations. This technological leap has opened up new avenues for research in diverse biomedical fields. Despite significant progress, there remains a critical need for new experimental methodologies for harnessing LRS technologies, new computational tools for interpreting LRS data, and demonstration of their applications to basic, translational, and clinical research.

We are pleased to announce a special issue on “Long-read Sequencing” in GPB. Guest editors for this special issue are Dr. Yi Xing (Children's Hospital of Philadelphia & University of Pennsylvania), Dr. Hui Shen (Van Andel Institute), and Dr. Wanlu Liu (Zhejiang University). This special issue will publish articles focusing on LRS-based experimental methodologies, computational tools, and their applications. This special issue seeks to provide a forum for disseminating latest technological advances and biomedical discoveries in LRS.

Topics may include (but are not limited to):

• Novel experimental methodologies for LRS-based DNA and RNA analysis.

• Novel computational algorithms, workflows, databases, and web servers dedicated to the analysis and visualization of LRS data.

• Integration of LRS with other omics approaches, such as single-cell or spatial omic technologies.

• Comparative analyses demonstrating the strengths and weaknesses of LRS in contrast to short-read sequencing.

• Applications of LRS to basic, translational, and clinical research.

Reviews, perspectives, original studies, databases, webservers, methods, application notes, protocols, etc. are all welcome. The portfolio will be open for incoming manuscripts until October 31, 2024.

Manuscripts should be prepared according to the Guide for Authors (https://academic.oup.com/gpb) and the manuscript template (http://gpb.big.ac.cn), and submitted online at https://www.editorialmanager.com/gpb/. Please indicate in the cover letter that the submission is for this special issue and provide the actual article type, while selecting “SI: Long Read Sequencing” as the article type during manuscript submission.

For further information, please contact us at:

Dr. Yi Xing (xingyi@chop.edu);
Dr. Hui Shen (Hui.Shen@vai.org);
Dr. Wanlu Liu (wanluliu@intl.zju.edu.cn);
Editorial Office (editor@big.ac.cn).