August 2 (Wednesday) Location: 会议楼1层

8:30–12:00

Arrival and Registration

Opening Remarks

14:00–14:30

Chair: Jun Yu

Session I: Fine Genome Assembly

14:30–16:15

Moderator: Kai Ye

14:30–14:55

Zhancheng Gao (Peking University People’s Hospital, China)

The complete diploid T2T reference genome of a Chinese Han

14:55–15:20

Jue Ruan (Agricultural Genomics Institute at Shenzhen, CAAS, China)

Concerns in the development of sequence assembly algorithms

15:20–15:45

Chuan-Le Xiao (Sun Yat-sen University, China)

A high-efficiency diploid 3D human genome reconstruction approach

企业报告

林伟 深圳市真迈生物科技有限公司 中国区营销总监

报告题目：国产测序平台助力基因组学的应用与发展

胡松年 中国科学院微生物研究所 研究员，博士生导师

TBD

16:15–16:30

Break

16:30–17:20

Moderator: Jingfa Xiao

16:30–16:55

Xiaofei Yang (Xi’an Jiaotong University, China)

The dynamic evolution of Papaver species driven by the birth and death of centromeres

16:55–17:20

Ming Xiao (Sichuan University, China)

CpG island detection, methylation pattern, and comparative difference analysis of the Chinese T2T genome

17:20–18:25

优选青年报告 (I) — Flash talks

Moderators: Lina Ma, Lei Gao

17:20–17:25

Ningbo Chen (Northwest A&F University, China)

History and unique evolutionary adaptation of indicine cattle

17:25–17:30

Shiyu Qiao (Institute of Vertebrate Paleontology and Paleoanthropology, CAS, China)

Genetic history and adaptive gene evolution of populations in Northern East Asia from the Late Pleistocene to the Holocene

17:30–17:35

Danni Guo (Tsinghua Shenzhen International Graduate School, Tsinghua University, China)

Skin microbiome is a strong indicator of aging: multi-omics evidence from a cohort of Chinese women with the same physiological age

17:35–17:40

Qianqian Peng (Shanghai Institute of Nutrition and Health, CAS, China)

Analysis of blood methylation quantitative trait loci in East Asians identifies ancestry-specific effects associated with complex trait variation

17:40–17:45

Qiuchen Meng (Tsinghua University, China)

The full set of potential open regions (PORs) in the human genome defined by consensus peaks of ATAC-seq data

17:45–17:50

Kun Wang (Shenzhen Institute of Advanced Technology, CAS, China)

PhyloVelo enhances single-cell velocity mapping using monotonically expressed genes

17:50–17:55

Guanshen Cui (Beijing Institute of Genomics, CAS / China National Center for Bioinformation, China)

Spatiotemporal transcriptomic atlas reveals the dynamic characteristics and key regulators of planarian regeneration

17:55–18:00

Shaosen Zhang (Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China)

Impact of crosstalk between epithelial cells and fibroblasts in cancer development and progression

18:00–18:05

Mengsha Tong (Xiamen University, China)

Prioritizing prognostic-associated subpopulations and individualized recurrence risk signatures from single-cell transcriptomes of colorectal cancer

18:05–18:10

Ziyi Wu (Second Military Medical University, China)

Spatial-temporal heterogeneity and clonal evolution for prostate cancer in China

18:10–18:15

Yang Guo ( Lanzhou University, China)

Differential analysis of m⁶A sites via incorporating region-specificity of m⁶A antibody

18:15–18:20

Chun-Chun Gao (Beijing Institute of Genomics, CAS / China National Center for Bioinformation, China)

scm⁶A-seq reveals single-cell landscapes of the dynamic m⁶A during oocyte maturation and early embryonic development

18:20–18:25

Yong Huang (Tsinghua University, China)

Predict the RNA secondary structure and cotranscriptional folding using Nanopore sequencing

18:30–20:30

Dinner

20:30–21:30

墙报展示

Moderators: Lina Ma, Lei Gao

August 3 (Thursday) Location: 会议楼1层

Session II: Omics and Big Data for Medicine / the 3rd Summit Forum of Population Genomic Research

8:25–8:30

Opening Remarks

Chair: Hui Jiang

8:30–10:05

Moderator: Yi Xing

8:30–9:15

Keynote

Qiaomei Fu (Institute of Vertebrate Paleontology and Paleoanthropology, CAS, China)

Insights into the East Asian population history over the past 100,000 years through ancient genomes

9:15–9:40

Sijia Wang (Shanghai Institute of Nutrition and Health, CAS, China)

The genetic basis and pleiotropic nature of human physical traits

9:40–10:05

Hui Jiang (MGI Tech Co., Ltd & University of Chinese Academy of Sciences, China)

Multi-omics technologies and platforms for population genome

10:05–10:20

Break

10:20–12:00

Moderator: Hui Shen

10:20–10:45

Zhenglong Gu (Greater Bay Area Institute of Precision Medicine (Guangzhou), China)

Mitochondrial DNA mutation and disease: young and old

10:45–11:10

Youqiong Ye (Shanghai Jiao Tong University School of Medicine, China)

Constructing a tumor high-precision spatial analysis system to reveal the immune-barrier boundary determining immunotherapy efficacy

11:10–11:35

Wanlu Liu (Zhejiang University, China)

Disease-associated human TCR characterization by deep learning framework TCR-DeepInsight

11:35–12:00

Zhang Zhang (Beijing Institute of Genomics, CAS / China National Center for Bioinformation, China)

CNCB-NGDC database resources: from deposition to integration to translation

12:00–13:30

Break

13:30–15:05

Moderator: Zhang Zhang

13:30–14:15

Keynote

Tao Jiang (Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, China)

Advances in molecular pathology and targeted therapies for gliomas: insights from the Chinese Glioma Genome Atlas

14:15–14:40

Yanmei Dou (Westlake University, China)

Decoding human development and non-cancer diseases by mosaic mutations

14:40–15:05

Mo Chen (Tsinghua University, China)

A temporal control of transcriptional program that distinguishes malignancy from tissue regeneration

15:05–15:20

Break

15:20–16:35

Moderator: Wanlu Liu

15:20-15:45

Hui Shen (Van Andel Institute, USA)

New single-cell tools for studying cancer ‘epigenetics’

15:45-16:10

Yi Xing (Children’s Hospital of Philadelphia and University of Pennsylvania, USA)

Long-read strategies to study the human transcriptome

16:10–16:35

Chen Chen (Biomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, China)

Enhanced understanding on intra-host evolution of pathogens

16:35–16:40

论坛结语

16:40–17:50

优选青年报告 (II) — Short talks

Moderators: Ying Yang, Lei Gao

16:40–16:50

Hu Fang (Shenzhen University, China)

Ganciclovir-induced mutations elevate the risk of a diverse spectrum of cancers in post organ transplant patients

16:50–17:00

Yuanhui Mao (Zhejiang University, China)

High-resolution Ribo-seq reveals widespread ribosomal frameshifting at the early stage of elongation

17:00–17:10

Yongsheng Li (Harbin Medical University, China)

Shedding light on the hidden human proteome expands immunopeptidome in cancer

17:10–17:20

Jinkai Wang (Sun Yat-sen University, China)

Single-cell and isoform-level characterization of m6A RNA modification

17:20–17:30

Junchao Shi (Beijing Institute of Genomics, CAS / China National Center for Bioinformation, China)

Exploring the expanding universe of small RNA

17:30–17:40

Cuiping Pan (Fudan University, China)

DNA methylation predicts adverse outcomes of coronary artery disease

17:40–17:50

Minxian Wang (Beijing Institute of Genomics, CAS / China National Center for Bioinformation, China)

A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease

17:50–18:00

GPB期刊报告

18:00–18:30

中国生物信息学十大进展颁奖 (2018–2022)

Moderator: Songnian Hu

18:30–20:30

欢迎晚宴

20:30–21:30

墙报展示

Moderators: Ying Yang, Lei Gao

August 4 (Friday) Location: 会议楼1层

Session III: Frontiers and Applications of Omics Technologies

8:25–8:30

Opening Remarks

8:30–10:15

Moderator: Fangqing Zhao

8:30–9:15

Keynote

Rong Fan (Yale University, USA)

Spatial multi-omics sequencing to study human physiology, aging, and disease

9:15–9:40

Junbin Qian (Zhejiang University School of Medicine, China)

Single-cell profiling reveals mechanisms of the bone barrow microenvironment homeostasis imbalance in osteopetrosis

9:40–10:05

Xun Xu (BGI-Research, China)

Stereo-Omics Technology and Application

企业报告

田仕林 北京诺禾致源科技股份有限公司 首席科学家，研究员职称。

TBD

10:15–10:30

Break

10:30–11:55

Moderator: Chang Chen

10:30–10:55

Xushen Xiong (Zhejiang University, China)

Epigenetic dissection of genetic underpinnings and regulatory circuitry in human diseases

10:55–11:20

Zeping Hu (Tsinghua University, China)

Deciphering metabolic reprogramming in diseases by multi-omics analyses

11:20–11:45

Jing Li (Naval Medical University, China)

Pathogenic germline variants in Asian pancreatic adenocarcinoma

企业报告

胡芳芳 Element Bioscience 商务总监、市场总监

TBD

11:55–13:30

Break

13:30–15:55

Moderator: Rong Fan

13:30–14:15

Keynote

Xueji Zhang (Shenzhen University, China)

Artificial intelligence biosensor: challenges and prospects

14:15–14:40

Chang Chen (Shanghai Institute of Microsystem and Information Technology, CAS, China)

Customizable silicon photonic chips for single molecule sensing and sequencing

14:40–15:05

Zhiwei Cao (Fudan University, China)

Computation and application of Ab-Ag molecular recognition

1505–15:30

Fangqing Zhao (Beijing Institutes of Life Science, CAS, China)

High-resolution spatially resolved proteomics of complex tissues

15:30–15:55

Tingting Li (Peking University Health Science Center, China)

Aberrant phase separation drug target discovery and interference — based on artificial intelligence

15:55–16:30

GPB创刊20周年纪念活动

Moderator: Xiangdong Fang

16:30–17:00

闭幕式，墙报和Flash talk颁奖

Moderator: Jun Yu

Session IV: AI and Application of Omics Data

8:25–8:30

Opening Remarks

8:30–10:15

Moderator: Feng Gao

8:30–9:15

Keynote

Jing-Dong Jackie Han (Peking University, China)

AI and aging

9:15–9:40

Qiangfeng Cliff Zhang (Tsinghua University, China)

Spatial transcriptomics data analysis via neighbor-aware cell embedding reveals cell communities with characteristic cell–cell interactions

9:40–10:05

Min Li (Central South University, China)

Computational methods for identifying 3D genome structures

10:15–10:30

Break

10:30–11:55

Moderator: Ge Gao

10:30–10:55

Kai Ye (Xi’an Jiaotong University, China)

SVision: a deep learning approach to resolve complex structural variants

10:55–11:20

Jianhua Yao (Tencent AI Lab, China)

Research and applications of artificial intelligence in genomic computing

11:20–11:45

Jun Wang (Institute of Microbiology, CAS, China)

Deep learning-based mining of functional peptides from metagenome

企业报告

杜怀亮 浪潮信息北京公司副总经理

TBD

11:55–13:30

Break

13:30–15:30

Moderator: Yi Xing

13:30–14:15

Keynote

Yaoqi Zhou (Shenzhen Bay Laboratory, China)

RNA structure prediction: overcoming a multi-front challenge

14:15–14:40

Qi Liu (Tongji University, China)

The “big model” and “small sample learning” for AI-driven omics data analysis

14:40–15:05

Shihua Zhang (Academy of Mathematics and Systems Science, CAS, China)

Intelligent spatial transcriptomics: paving the way for deciphering tissue architecture

1505–15:30

Ge Gao (Peking University, China)

Delineate the regulatory map in silico

15:55–16:30

GPB创刊20周年纪念活动

Moderator: Xiangdong Fang

16:30–17:00

闭幕式，墙报和Flash talk颁奖

Moderator: Jun Yu